Peptide Research Guides & Protocols

• NAD+ (Nicotinamide Adenine Dinucleotide) Monograph: Sirtuin Deacetylation, PARP-1 DNA Repair, and Mitochondrial Respiration — A comprehensive biochemical review of NAD+ coenzyme dynamics, evaluating SIRT1-SIRT6 activation, PARP-1 base-excision DNA repair, Complex I electron transport, and age-related CD38 enzymatic consumption.
• MOTS-c (Mitochondrial ORF of 12S rRNA Type-c): Retrograde Signaling, AMPK Phosphorylation & Metabolic Homeostasis — A comprehensive biochemical review of the 16-amino-acid mitochondrial-derived peptide MOTS-c, evaluating retrograde mitochondrial-nuclear signaling, AICAR-independent AMPK activation, folate cycle inhibition, and muscle glucose uptake.
• Epithalon (Ala-Glu-Asp-Gly) Monograph: Telomerase Reverse Transcriptase (TERT) Induction, Pineal Function & Epigenetic Longevity — A definitive scientific analysis of the synthetic tetrapeptide Epithalon (Ala-Glu-Asp-Gly), detailing telomerase reverse transcriptase (TERT) induction, pineal melatonin regulation, chromatin decondensation, and cellular senescence attenuation.
• Semax & Selank Heptapeptides: Comparative Review of BDNF/TrkB Signaling, Enkephalinase Inhibition & Neurochemical Modulation — A comprehensive biochemical review of synthetic regulatory heptapeptides Semax and Selank, evaluating brain-derived neurotrophic factor (BDNF) expression, TrkB receptor activation, enkephalinase inhibition, and neurotransmitter turnover in neuroscience models.